网状内皮组织增殖病病毒免疫抑制状态下禽波氏菌对雏鸡致病性增强

doi:10.11843/j.issn.0366-6964.2017.08.016

Abstract

Abstract:

Bordetella avium (B. avium) can cause a highly contagious disease of upper respiratory tract of poultry and often co-infect with immunosuppressive viruses. In order to study the effect of immunosuppressive state on pathogenicity of B. avium, chick embryos were inoculated with reticuloendotheliosis virus (REV) and infected with B. avium after they were hatched. The body weight, immune organ index, NDV antibody level, B. avium antibody level, the invasion time point of B. avium in different tissues, histopathological changes, and secondary infections of other bacteria were observed respectively under co-infection and simple infection. The results showed that REV caused severe growth inhibition and immunosuppression in chicks which were aggravated by B. avium infection. At the same time, the antibody level of B. avium was interfered. The detection time of B. avium in the liver, heart and kidney of chicks in the immunosuppressive state was 1 d earlier than that in B. avium simple infection group. Chick tracheal mucosa completely fell down and extensive necrosis appeared in liver, heart and other tissues in co-infection group. And the number of secondary infection cases was significantly increased. In conclusion, in the REV immunosuppressive state, the body defense system of chick is destroyed, and the immune response to B. avium decreased. At the same time it provides convenient for the invasion and spread of B. avium in tissues, so the pathogenicity of Bordetella avium increased in the immunosuppressive state induced by REV.

CLC Number:

S852.61

YANG Ping-ping, YUAN Peng, WEI Kai, HU Li-ping, ZHU Rui-liang. Increased Pathogenicity of Bordetella avium in the Immunosuppressive State Induced by Reticuloendotheliosis Virus[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2017, 48(8): 1511-1518.

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References

[1] WANG C W, LIU L P, ZHANG Z, et al. Immunological and protective effects of Bordetella bronchiseptica subunit vaccines based on the recombinant N-terminal domain of dermonecrotic toxin[J]. Int Immunopharmacol, 2015, 28(2):952-959.
[2] SRIGLEY J A, GOLDFARB D M, PERNICA J M. Bordetella species other than Bordetella pertussis[J]. Clin Microbiol Newsletter, 2015, 37(8):61-65.
[3] 李洪广, 王芳, 姜平, 等. 兔支气管败血波氏杆菌PRN基因缺失突变株的构建及特性研究[J]. 畜牧兽医学报, 2012, 43(2):299-305.
LI H G, WANG F, JIANG P, et al. Construction of defined mutations of PRN of rabbit Bordetella bronchiseptica and property research[J]. Acta Veterinaria et Zootechnica Sinica, 2012, 43(2):299-305. (in Chinese)
[4] 覃娟娟, 顾凡, 蔡雨涵, 等. 副猪嗜血杆菌毒力菌株和猪支气管败血波氏杆菌毒力菌株双重PCR检测方法的建立及应用[J]. 中国兽医学报, 2015, 35(8):1217-1222.
QIN J J, GU F, CAI Y H, et al. Establishment and application of duplex PCR for detecting virulent strains of Haemophilus parasuis and Bordetella bronchiseptica[J]. Chinese Journal of Veterinary Science, 2015, 35(8):1217-1222. (in Chinese)
[5] BEACH N M, THOMPSON S, MUTNICK R, et al. Bordetella avium antibiotic resistance, novel enrichment culture, and antigenic characterization[J]. Vet Microbiol, 2012, 160(1-2):189-196.
[6] LOKER S B, TEMPLE L M, PRESTON A. The Bordetella avium BAV1965-1962 fimbrial locus is regulated by temperature and produces fimbriae involved in adherence to turkey tracheal tissue[J]. Infect Immun, 2011, 79(6):2423-2429.
[7] SEBAIHIA M, PRESTON A, MASKELL D J, et al. Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction[J]. J Bacteriol, 2006, 188(16):6002-6015.
[8] MIYAMOTO D M, RUFF K, BEACH N M, et al. Bordetella avium causes induction of apoptosis and nitric oxide synthase in turkey tracheal explant cultures[J]. Microbes Infect, 2011, 13(10):871-879.
[9] MORENO L Z, KNÖBL T, GRESPAN A A, et al. Draft genome sequence of Bordetella avium Nh1210, an outbreak strain of lockjaw syndrome[J]. Genome Announc, 2015, 3(2):e00120-15.
[10] RAFFEL T R, REGISTER K B, MARKS S A, et al. Prevalence of Bordetella avium infection in selected wild and domesticated birds in the eastern USA[J]. J Wildlife Dis, 2002, 38(1):40-46.
[11] NOVIKOV A, SHAH N R, ALBITAR-NEHME S, et al. Complete Bordetella avium, Bordetella hinzii and Bordetella trematum lipid A structures and genomic sequence analyses of the loci involved in their modifications[J]. Innate Immun, 2014, 20(6):659-672.
[12] 谭燕玲, 朱瑞良, 王慧, 等. 鸡胚胎性病原菌多重PCR检测方法的建立[J]. 中国预防兽医学报, 2011, 33(5):374-377.
TAN Y L, ZHU R L, WANG H, et al. Establishment of multiplex PCR detection for pathogens of chicken embryos[J]. Chinese Journal of Preventive Veterinary Medicine, 2011, 33(5):374-377. (in Chinese)
[13] FILION R, CLOUTIER S, VRANCKEN E R, et al. Infection respiratoire du dindonneau causée par un microbe apparenté au Bordetella bronchiseptica[J]. Can J Comp Med Vet Sci, 1967, 31(5):129-134.
[14] 朱瑞良, 张绍学, 唐珂心. 鸡波氏杆菌病研究初报[J]. 山东农业大学学报, 1991, 22(1):91-94.
ZHU R L, ZHANG S X, TANG K X. Primary study on the disease caused by Bordetella avium in chickens[J]. Journal of Shandong Agricultural University, 1991, 22(1):91-94. (in Chinese)
[15] LIANG M F, ZHAO Q Y, LIU G H, et al. Pathogenicity of Bordetella avium under immunosuppression induced by Reticuloendotheliosis virus in specific-pathogen-free chickens[J]. Microb Pathog, 2013, 54:40-45.
[16] GUO F X, XUE C, WU C, et al. Effects of polysaccharide on chicks co-infected with Bordetella avium and Avian leukosis virus[J]. Carbohydr Polym, 2014, 109:71-76.
[17] LIU L P, YU C L, WANG C W, et al. Immuno-enhancement of Taishan Pinus massoniana pollen polysaccharides on recombinant Bordetella avium ompA expressed in Pichia pastoris[J]. Microb Pathog, 2016, 95:54-61.
[18] ZHU F J, LIU X, SUN Z H, et al. Immune-enhancing effects of Taishan Pinus massoniana pollen polysaccharides on DNA vaccine expressing Bordetella avium ompA[J]. Front Microbiol, 2016, 7:66.
[19] ZHAO X, LIANG M F, YANG P P, et al. Taishan Pinus massoniana pollen polysaccharides promote immune responses of recombinant Bordetella avium ompA in BALB/c mice[J]. Int Immunopharmacol, 2013, 17(3):793-798.
[20] FAIZ N M, CORTES A L, GUY J S, et al. Efficacy of various Marek's disease vaccines protocols for prevention of Marek's disease virus-induced immunosuppression[J]. Vaccine, 2016, 34(35):4180-4187.
[21] 李凯, 高立, 祁小乐, 等. 禽网状内皮组织增生病病毒感染对SPF鸡免疫器官和疫苗免疫效果的影响[J]. 畜牧兽医学报, 2016, 47(2):340-345.
LI K, GAO L, QI X L, et al. The influence of reticuloendotheliosis virus infection on immune organs and immune efficacy in SPF chickens[J]. Acta Veterinaria et Zootechnica Sinica, 2016, 47(2):340-345. (in Chinese)
[22] 陈瑞爱, 李延鹏, 郭凯, 等. 禽网状内皮组织增生症病毒p30-gp90串联表达蛋白及其免疫原性[J]. 微生物学报, 2014, 54(3):352-358.
CHEN R A, LI Y P, GUO K, et al. Immunogenicity of co-expressed p30-gp90 against reticuloendotheliosis virus[J]. Acta Microbiologica Sinica, 2014, 54(3):352-358. (in Chinese)
[23] 庄萍萍, 王小满, 孟薇, 等. 网状内皮增生症病毒感染改变外泌体蛋白质组成和免疫调节功能[J]. 中国细胞生物学学报, 2016, 38(6):682-690.
ZHUANG P P, WANG X M, MENG W, et al. The infection of reticuloendotheliosis virus changed the protein composition and immunomodulation of exosome[J]. Chinese Journal of Cell Biology, 2016, 38(6):682-690. (in Chinese)
[24] 王一新, 栾怀彪, 许书珍, 等. 禽网状内皮组织增生症病毒LN1201株的全基因组序列分析及其U3区的独特性[J]. 中国预防兽医学报, 2016, 38(11):855-859.
WANG Y X, LUAN H B, XU S Z, et al. Genome analysis of a reticuloendotheliosis virus and the unique insertion in U3 region[J]. Chinese Journal of Preventive Veterinary Medicine, 2016, 38(11):855-859. (in Chinese)
[25] 杨萍萍, 刘静静, 赵雪, 等. 间接免疫酶组化检测禽波氏杆菌在感染鸡体内的抗原定位[J]. 中国兽医学报, 2013, 33(12):1832-1837.
YANG P P, LIU J J, ZHAO X, et al. Study on localization of Bordetella avium in infected chickens by indirect immunoperoxidase technique[J]. Chinese Journal of Veterinary Science, 2013, 33(12):1832-1837. (in Chinese)
[26] 郭繁霞, 朱瑞良, 吴村, 等. B亚型禽白血病病毒所致免疫抑制条件下共感染禽波氏杆菌对雏鸡的影响[J]. 中国兽医学报, 2014, 34(7):1072-1077, 1093.
GUO F X, ZHU R L, WU C, et al. Effect of pathogenicity of Bordetella avium under immunosuppression induced by avian leukosis virus in chickens[J]. Chinese Journal of Veterinary Science, 2014, 34(7):1072-1077, 1093. (in Chinese)
[27] 梁漫飞, 朱瑞良, 高秀妹, 等. 禽波氏杆菌与REV共感染对SPF鸡免疫系统的影响[J]. 中国兽医学报, 2013, 33(6):833-837.
LIANG M F, ZHU R L, GAO X M, et al. Effects of co-infection of REV and B. avium on immune system in SPF chicken[J]. Chinese Journal of Veterinary Science, 2013, 33(6):833-837. (in Chinese)

Increased Pathogenicity of Bordetella avium in the Immunosuppressive State Induced by Reticuloendotheliosis Virus

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